Open source · MATLAB

Finite-element modeling
for EEG and MEG.

Zeffiro Interface is MATLAB software for a tetrahedral volume conductor: import tissue surfaces, mesh, assemble a lead field, and reconstruct sources. The same pipeline covers EIT and TES. Source is GPL-3.0.

Explore Zeffiro See list of papers
Translucent head model with cortical activation and an EEG electrode lattice. Finite-element mesh overlaid on the head model. EEG electrode cap on the head model. Localized neural source reconstruction inside the head.

Layered views

The pipeline

Grayscale sagittal MRI of a human head.
01 MRI / Atlas
Color-coded tissue segmentation of a head model.
02 Segmentation
Finite-element mesh of a human head.
03 FEM Mesh
Head conductivity map.
04 Conductivity
Lead-field sensitivity on a head model.
05 Lead Field
Inverse reconstruction hotspot on a brain slice.
06 Inverse Solver
Cortical source image with a localized activation.
07 Source Image

One framework.

Many ways
to solve.

Deterministic, Bayesian, sparse and dynamic methods — all in one unified environment.

Browse all methods →

Deterministic

  • MNE
  • dSPM
  • sLORETA
  • eLORETA
  • LCMV Beamformer
  • Dipole Scan

Bayesian

  • IAS
  • RAMUS
  • ClassGMM

Sparse

  • Group Lasso
  • HALpR

Dynamic

  • Kalman
  • UKF / NMM
  • ClassKF

See Zeffiro in action

Sagittal multicompartment head model.
Multicompartment
FEM model
Lead-field sensitivity with scalp electrodes.
Accurate
lead fields
Cortical source reconstruction.
Cortical source
reconstruction
Deep source localization inside a translucent head.
Deep source
localization
Multichannel EEG time series.
Time-resolved
analysis
Class + plugin Inverse tracks
EEG/MEG/EIT/TES Forward problems
R2023a+ MATLAB
GPL-3.0 License